There are truly worthwhile and cost effective vaccine therapies in the pipeline. They will deliver on the potential of DNA vaccine technology that is now approaching market. These DNA vaccines will demonstrate far greater efficacy than anything we have yet seen.
Moreover, DNA vaccines can be used against diseases other than their historical target, which has been viruses. Early on, it dawned on researchers that this new generation of vaccines could be used to train the immune system to attack cancers and a wide range of other malignancies that act like foreign invaders inside the body.
Conventional vaccines work by having the body’s immune system recognize unique antigenic proteins that are part of the virus, triggering an immune response against the invader. The elegance of DNA vaccines is that, rather than introducing into the body an actual virus, only the antigen, that would be recognized as foreign, is introduced. Scientists realized that they could turn cells in the body into protein-manufacturing plants. By isolating the DNA responsible for producing ONLY the foreign antigenic protein associated with a specific virus, they could get around various issues associated with live or weakened viruses.
Scientists create ring-shaped DNA plasmids that contain the genetic code for the antigen and then introduce the plasmid into cells of the body. Once inside, the plasmids migrate to the nucleus. There, they could direct the cell’s own molecular machinery to build the desired antigenic protein(s). When secreted by the cells, these proteins, which match antigens associated with the targeted disease causing virus, or cancer, trigger a preventive and or therapeutic immune response.
When the immune system encounters the antigens produced by DNA vaccines, it learns to recognize and eliminate them efficiently. From that point, the immune system can mount a defense against these disease proteins. These defenses can, in theory, protect the body from cancers, Alzheimer’s and other conditions.
Big Pharma companies as well as national labs and academic research facilities poured billions into a first wave attempt at producing commercially viable DNA vaccines. Problems delivering the DNA vaccines in a way that provoked a sufficient immune response, soon dampened their enthusiasm.
Two basic problems prevented the development of truly effective DNA vaccines. The first was an immature understanding of genetics. In those days, researchers were only beginning to learn how to optimize the DNA sequences to produce antigens with maximum impact. The second issue was the familiar delivery problem. Cells did not absorb enough of the DNA plasmids to become effective antigen factories. Since the amount of antigens produced by the body was therefore low, the immune response was insufficient to form the basis of viable drugs.
As a result, early DNA vaccine trials in humans were disappointing. The flow of research dollars slowed. Behind the scenes, however, determined scientists in dedicated startups never lost confidence in the core science. As importantly, alliances were formed and diverse discoveries merged. In recent years, their work has finally begun to bear fruit.
One such company has a patent protected technology that has wide applicability to treat cancers at a fraction of the currently marketed therapy that has a sticker price of nearly $100,000. This company, and a few others, are delivering truly disruptive breakthroughs and will be unlocking electrifying profit potential with DNA vaccines.
Just as DNA vaccines have finally begun to bear fruit, so too are advances in being able to control our aging process.
As mentioned in a previous post on this blog, Dr. Sanjay Gupta, Chief Medical Correspondent at CNN, has reported that “Practical Immortality may now be within our grasp.”
So now the question becomes, “how do we slow the rate of aging and avoid the frailty that would make longevity less desirable?”
With antioxidant supplements, we can slow our rate of aging; with a nutrition and fitness routine, we can avoid frailty and improve our health; and with an industry leading home business opportunity, we can make great money and generate financial wealth.
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Happy Reading and Here's to Your Success! Mike Farrell, founder, owner, and operator of aspenIbiz, my portfolio of Internet Marketing companies.
Finally, I want to thank Patrick Cox of Agora Financial as he was the source of some of the materials about the technology advancements mentioned in this post.
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